Search on: IMMUNOLOGIC ADJUVANT 
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Descriptor English:   Adjuvants, Immunologic 
Descriptor Spanish:   Adyuvantes Inmunológicos 
Descriptor Portuguese:   Adjuvantes Imunológicos 
Synonyms English:   Adjuvant, Immunologic
Adjuvants, Immunological
Immunologic Adjuvants
Immunological Adjuvant
Adjuvant, Immunological
Immunologic Adjuvant
Immunological Adjuvants
Immunoactivators
Immunopotentiators
Immunostimulants
Immunoadjuvants  
Tree Number:   D27.505.696.477.067
Definition English:   Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. 
Indexing Annotation English:   DF: ADJUVANTS IMMUNOL
See Related English:   Adjuvants, Pharmaceutic
 
History Note English:   65 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
EC economics GE genetics
HI history IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   27905 
Unique Identifier:   D000276 

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